I can't say I've tried effects, etc. to make the channels distinctly different, but I have had the opportunity to play in stereo - F2B, Mackie FR-1400, and 2 Eden D210XST (extended frequency low end with frightening efficiency). Separating the cabinets creates a very pleasing sound field that, to my ears, highlights the sonic nuances of an Alembic.
Of course 99% of that is lost when the rest of the band starts to play, but I know what it can/is doing.
Which reminds me of an interesting conversation I had with a very knowledgeable Alembic dealer who shall remain nameless. He didn't know I was a player, and I just asked him what was popular. He pointed out that different genres tend toward different high end instruments (of which he had almost all of them), but at the end of the day, Alembic remained at the pinnacle of sonic technology.
He went on to point out that even with the best amplification/speaker equipment, you couldn't hear the complete sonic capabilities of an Alembic, i.e. the amplification technology still isn't as good as the Alembic pickup/electronics package, and that you really needed a great recording setup to actually hear what an Alembic is capable of.
I think owning an Alembic is about beginning with the best of the best and striving to build an amplification chain that maintains that tone, knowing that any chain will color and ultimately deteriorate the source.
I actually have experienced what the dealer was describing. A couple of years ago I was working on a difficult passage, and I recorded it to figure out what I was doing wrong. Exploiter/Spoiler into a Brick preamp into a nice digital recorder. When I played it back through a nice set of headphones, even though it was just a rough practice take, I was startled by the superior sound and tone I heard. I could literally hear things that were lost in amplification.
Apologies for the long post. To sum up:
1. Do play your Alembic through a stereo rig if you get the chance
2. When the band starts playing it probably won't matter
3. Don't pass up the chance to record your Alembic to really hear what it's capable of