I have a F-2B & SF-2, so here's my 2 cents. I run a sort of hybrid stereo/mono setup. My DS-5R is set to stereo & I run each pickup to a separate channel on the F-2B, I then come out of the F-2B from the Mix(mono) jack into the SF-2 channel A input & out of the SF-2 channel B output into one channel of a QSC GX7. I have one channel of the SF-2 set for Band Pass & use it to dial in the room to get the best low end punch for that venue. I rotate the frequency control on that channel about 1/8 turn up or down to find the sweet spot to get the fat kick drum attack on my low end, then use the filter gain to set how much I need to enhance the sound. I run the other channel of the SF-2 in High Pass mode & use it to enhance the upper mids & highs for more clarity. So I use the EQ on each channel of the F-2B to EQ each pickup separately, & use the SF-2 as an overall tone enhancer for both pickups & to dial in the room. The SF-2 is almost like an auto correct like you would use on a photo to make it more vivid. It takes the already great sound from the F-2B & really makes it stand out.
When I first got my F-2B I was using the power amp section of my Eden WT 800 to power Eden D410 XLS & D 115 XLT cabinets. When I got my QSC GX7 it was a noticeable difference in sound, MUCH cleaner! I have since switched to AccuGroove 3 & 4 way cabinets & now my rig is so much more responsive to minute tweaks! If you really want to appreciate the full spectrum Alembics are capable of, I can't recommend AccuGroove enough! The made my Eden boxes sound like they had pillows strapped to the front of them!