Hipshot makes many models of DeTuners. Your Alembic either has a Gotoh or Schaller head, so they definitely will have exact replacement models that won't require drilling extra back holes or boring out the main hole.
When they make the Hipshot tuner, they start with the same kind of head that you have now. The body of the tuner is mounted on a plate that has the lever mechanism, and they have to cut the string shaft and lengthen it to accomodate the extra depth of the plate. The plate is bigger than the footprint of the tuner, but they put the screw holes in the same place.
I've got Hipshots on a couple of basses (Musicman Stingray, Warwick Thumb, and an SSD Spector) and I would agree with dela217 - it's a winner dropping to D, but beyond that you'll probably find that it just doesn't work that well.
The action is smooth and nice on all the basses except the Warwick. On that instrument, the tuners are angled in close to the headstock, so the pivoting action of the lever is severely limited.
