I remember when Monster Cable brought out a line of very expensive high-end guitar cables in the mid-80s. I was working with Lee Ritenour at the time and they
gave him a couple (yes, that's how many Artists operate). I think he didn't like them because they were impractically heavy - thicker than our original Belden 4-conductor Series cables. So he gave me one and I made a few patch cords out of it. Difficult to solder because the individual strands were lacquer coated.

Too large for a standard 1/4" connector shell so that had to be modified.

Etc...
But I was trying to drink the kool-aid because of my audiophile leanings at that time. I think it's possible that a cable's specific materials, construction and insulating material might make the most difference with a high-impedance source like a standard passive guitar. Not as critical when the source is lo-z or a line-level signal.
Well, Monster Cable showed their hand completely when they followed this up by introducing specific "Rock" cables and different formula cables for "Jazz" and "Country". OMG people! And that was the end of my belief in the fairy-dust. Idiots.
It's tough to think an $8000 power cable for your tube amp wouldn't lead to rewiring your house and maybe trying to get bigger cable put in by your utility provider - all the way to the power plant. I'm sure that would improve my sound!
Jimmy J