Question for you - are you using the mono out from the F-2B, sending to two different amps,
Right now, I'm running it into ProTools, not using it live. I'm using the individual outputs so that I have the option of processing them separately, but so far, I've just combined them (effectively using the mono out!) and they sound really nice.
I rarely play the Series bass out, as we play mostly local pubs here in Galway just for the craic. In that situation, we often have people walking through the midst of us while we are playing as it is more of a session situation - no stage. The risk of an accident is higher that I'm willing to accept for the Series. I'm using the Orion for the pubs, and so far have had no issues. On the occasions where we are playing a larger venue, I have brought out the Series a few times, and may consider bringing the F-2B next time.