I'd be very surprised if you didn't need to at least tweak the intonation on a couple strings switching from Alembic rounds to D'A Chromes Growly... but it's easy-as-pie buddy.
Just use a good chromatic tuner, (I love my Polytune 2 strobe pedal for this) with the neck at rest,
important that nothing is influencing it forward or back here, completely at rest, then tune the string open. Then check at the 12th fret. Is it sharp? Adjust the saddle rearward. If it notes flat, adjust the saddle towards the nut. When it notes true, move up to the 24th fret. You're really splitting hairs up there, so be very patient. Keep checking the open string for tuning drift too. Spot check around the neck at intervals for accuracy. Expect a couple cents of drift... figure out what you can work with. 'Rinse and Repeat' for each string. After doing all 5, I like to go over them all again. Cause I'm incredibly OCD about stuff.
*another helpful hint, try as best you can to keep the other strings muted while intonating one... so you don't pick up any sympathetic tones through the tuner. Alembics are incredibly resonant creatures, and plucking one string often sets off a couple more harmonics. Great vibes when you're playing though a couple kilowatts of amp and speakers, not so much when trying to set intonation.
Hit me if you get stuck, man.
