I keep wanting to contribute to this thread - very interesting questions. What is the sound you are really looking for? Is it the sparkely top end that Alembics are famously capable of or is the Sire giving a classic Jazz Bass scooped sound (or something else)? My theory is that Alembics have a broader and flatter frequency response - as in, all the frequencies are well represented, modified of course by where you have the filter set. Whereas Fenders don't have the true low-end frequencies that Alembic do, but make up for it with a low-midrange bump and high-mid bump in P basses, with more of a mid-scoop with J basses.
I think the Ampeg stuff doesn't necessarily work for the glassy sparkle that a cleaner, more full-range preamp might give, but take my opinion with a grain of salt, I have very limited experience with anything Ampeg. But the sparkle may not be what you're looking for either. Can you figure out what's different between the Sire & the Alembic? Sometimes the classic Fender design just naturally works for certain things, whether it's the bolt-on neck or the pickup configuration or something else. Plus, each Alembic is different, as opposed to the assembly line Fender consistency.