I think there was a thread somewhere about people doing this intentionally, but I couldn't find it.
Went to play a private party in the boondocks of NY State, a few hours from anything. Got there, plugged in all my stuff, no sound. I was using a little stompbox F2b knockoff preamp (didn't want to haul my rack out) into a tiny Demeter 800 watt power amp. The wall wart for the preamp didn't work.
Screwed, right?
Took a chance and plugged my custom series II direct into the power amp, turned up the gain a bit - and it sounded amazing! Crystal clear, balanced... I loved it.
i may do more playing like this (probably bring the real F2B just in case, though).