I have found to my ear The F1X with SF2 in the effects loop coupled with a PLX3400 sounds the best. I'm using Spoilers 4-5-6&7, Excel 5's, an SC Deluxe 4, Distillate 5, Rouge 5, (13 Alembics in all) as well as a Ric 4003, Tbird, Stambaugh 4, Ripper and an Ovation Acoustic/electric. I either use Epifani T310 - T115 cabs or Acme Low B2 and B4 cabs. But I mostly have to use a provided SVT rig when I play clubs. As has been stated in previous threads, your rig is really just an on stage monitor when you have a big system. That's why I like the DI on the F1X so at least I know the engineer is getting my source sound. I also liked the Glockenklang stuff I've tried at NAMM last year.
Danno