Dave will have to fill in the details, but perhaps I can give him a head start.
The ELF unit is itself a crossover. You can run a full range signal into it, then split the output to an ELF sub and a standard cab. Now, the crossover point and overlap are only adjustable by internal jumpers, and it's hard to find the documentation on that (I would love to have a copy, for the low end model, if anyone can oblige).
So one approach is to run a full signal into the ELF unit, then take the split outputs into two different amps (or channels), and out to the speakers. You have an option here, as to whether the input is mono or stereo, though the ELF sub output is summed-mono (the upper range output can be mono or stereo).
An alternative, which I happen to use, is to split before the ELF. I run the output from one channel of my SF-2 into the ELF but only use the sub-out (into one amp channel), and the other SF-2 output goes straight into the other amp channel, which drives my non-ELF cabinet full range.
So much for background, I haven't a clue what this means for reverb or other effects. I keep thinking I would like to use just a tiny smidgen of reverb (non-digital...), and if I ever get around to it, I would want it on the lows even more than the highs.
So I'm curious to hear more about the configuration here, and what it means to not get a clean tone.