I predict in less than 10 years, only us old-timers will know how to tune a guitar or bass.
Having typed that, can you imagine the possibilities of having your tuning on a midi channel for mid-song or mid-solo changes? The really difficult steel guitar licks? Neat-o.
Of course, when you completely blow the solo section of your trademark song of the night, you could always blame it on bad programming or a virus.. >
John