I have three of the 362's and I love them. They are in two bass rigs and a guitar rig. I run them first. I tried it both ways in the guitar rig, and it seemed confused by the delay, modulation, and reverb of the effects processor. So I put it first just to clean up the incoming signal. I like the P90 and single coil sound, so when the BBE makes things crisper and brighter, it suits my personal taste. It's the only thing in the effects loop of a Mesa M-Pulse 600 that drives two Mesa 115's, and it tightens up the 15's nicely (using a Rogue 5 with flatwounds). I also have it first in the effects loop of an F1-X, followed by a dbx 160A. I'm not an electronics guy, so I just think of it as cleaning up the incoming signal. I don't really know what's going on, though. Soundwise, the end result of a BBE for bass or guitar is tighter and brighter.