I play at a lot of fairly large rooms (300-500 people) and have to say that you need headroom, horsepower and clarity to get a great sound live. Both guitarists in my band use 100w tube half stacks and the drums are most often filled through a 2x15 and horn cab.
I have found that most bass gear sounds pretty honky and distorted even with the best brands. The weakest link in most bass cabs is the horn driver, I have consistently replaced the horn drivers in my cabinets first with JBL2402's and now with Beyma CP22 supertweeters. This makes an incredible difference to the audability of my sound onstage.
I have been using the Crown XTi4000 power amp for about two years now and recommend it highly. It is only and 20lbs and will deliver over 3000watts RMS bridged mono @4 Ohms or 1600watts a side into 2. I use mine at 4 Ohms a side (1200watts) into 2x4 Ohms cabinets. I am using a 6x10 loaded with Eminence Delta 10's (2400w RMS) with a 2x10 loaded with kappa 10's (1000w RMS).
However, if you just chuck your preamp in front of an XTi you will only get a fraction of what this amp can deliver. You absolutely MUST download the HiQnet System Software (free from Crown) and use the USB connection to program your own custom presets.
The Xti has 6 bands of fully parametric EQ with high and low pass filters, a fully configurable stereo crossover, inbuilt limiters and a host of other features which can be saved to one of 15 user presets. Every time I have read criticisms of the XTi's in forums it is by users who have not availed themselves of the advanced features this amp supports.
I have a preset just for the 6x10 in bridged mono mode and another two presets for Bi amp (big Stage),and full range (smaller stage) configurations with both cabinets.
http://www.crownaudio.com/amp_htm/xti.htm#specs