Jazzyvee,
I have experience with the Electro-Harmonix 22 Calibre amp. I was not happy with it. Yes, it's amazing that a little pedal-sized box can do what it does...it gets fairly loud... but... it goes into distortion very easily, and that distortion was not smooth and creamy. When I hooked it up to a real articulate speaker I was not happy with the sound the amp was sending. Another thing: E-H said the amp was compatible with a 4-ohm speaker, which turned out to be not true. I pinned them on it and they said I was correct. But they did not offer to take it back; they just said to try to return it to the dealer. Not good service.
Now they have a 44-watt version; perhaps it is far superior to the 22 Calibre. But I would need to be sure it was what I need and not trust what their ads say.
I wouldn't even bother to try it for bass guitar applications.
Ben