Hm (no pun intended), it sounds like a bad cable perhaps. Have you tried different cables?
Another possibility is a dirty contact in one of the switches. Plugging a cable in and out a bunch of times can fix this.
Another possibility might be a loose ground wire in the preamp. Not very likely in my opinion, but possible.
Maybe a tube gone bad? I've not heard of this symptom, but I guess it's possible.
Something like this might seem like it's the preamp, but it could be a bad cable from the bass or between the preamp and power amp or even between the preamp and PA. If it has just started out of the blue, those are the first places I would look.
Edwin