Rv - i use all sorts of virtual instruments. My go-to DAWs are Reason and Luna (and recently, almost exclusively Luna - when i need Reason instruments i use the reason rack as a plug in). Kontact (and lots of Kontact-friendly plugs), various sample players, soft synths, pianos, organs, things like that. My setup is clunky now - Brian Moore midi guit with a 13 pin out into Roland GI-20. The built in usb port on the Roland was giving me HUGE delay, so i got a midi DIN to usb cable - come out of the roland Midi out into my computer - way shorter latency, to the point where i can fingerpick and not lose the tempo. It works, but it's not elegant and i'd love to really get that latency as short as possible, with better tracking (esp on the low notes).